- E85.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2024 edition of ICD-10-CM E85.4 became effective on October 1, 2022.
- This is the American ICD-10-CM version of E85.4 – other international versions of ICD-10 E85.4 may differ.
ICD-10-CM E85.4 is grouped within Diagnostic Related Group(s):
- 545 Connective tissue disorders with mcc
- 546 Connective tissue disorders with cc
- 547 Connective tissue disorders without cc/mcc
Applicable To
- Localized amyloidosis
- Transthyretin-related (ATTR) familial amyloid cardiomyopathy
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2016 (effective 10/1/2015): No change
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2024 (effective 10/1/2022): No change
Diagnosis Index entries containing back-references to E85.4:
- with lung involvement > Amyloidosis (generalized) (primary) E85.9
- heart > Amyloidosis (generalized) (primary) E85.9
- liver > Amyloidosis (generalized) (primary) E85.9
- localized > Amyloidosis (generalized) (primary) E85.9
- organ limited > Amyloidosis (generalized) (primary) E85.9
- pulmonary > Amyloidosis (generalized) (primary) E85.9
- skin (lichen) (macular) > Amyloidosis (generalized) (primary) E85.9
- subglottic > Amyloidosis (generalized) (primary) E85.9
- amyloid > cerebral I67.9
- amyloidosis > in (due to) E22.0
- amyloidosis > in (due to) E22.0
- amyloid > Cardiomyopathy (familial) (idiopathic) I42.9
- transthyretin-related familial (ATTR) > amyloid E85.4
- transthyretin-related familial amyloid (ATTR) > Cardiomyopathy (familial) (idiopathic) I42.9
- artery, arterial (atheromatous) (calcareous) > Degeneration, degenerative
- cerebral, amyloid > artery, arterial (atheromatous) (calcareous) E85.4
- amyloid > cutis L98.8
- heart > Degeneration, degenerative
- amyloid > heart E85.4
- intestine, amyloid > Degeneration, degenerative
- amyloid > kidney N28.89
- amyloid > liver NEC (diffuse) K76.89
- amyloid > nervous system G31.9
- amyloid > skin L98.8
- amyloid > spinal (cord) G31.89
- amyloid > spleen D73.0
- amyloid > gastrointestinal (tract) K92.9
- amyloid > heart (organic) I51.9
- in > lung J98.4
- amyloidosis > in E85.4
- amyloid > spleen D73.9
- amyloidosis > glomerular (in) N05.9
- in (due to) > Glaucoma H40.9
- amyloidosis > in (due to) E85.4
- in (due to) > Glomerulonephritis N05.9
- amyloidosis > in (due to) E85.4
- amyloidosis > Lichen L28.0
- amyloid > Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic) N05.9
- in > Nephrosis, nephrotic (Epstein\’s) (syndrome) (congenital) N04.9
- amyloidosis > in E85.4
- amyloid, any site > Neuritis (rheumatoid) M79.2
- in (due to) > autonomic G90.9
- amyloidosis > in (due to) E85.4