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Free Medical Coding > ICD10 CM > 2025 ICD-10-CM Codes > 2025 ICD-10-CM Codes P00-P96 – Certain conditions originating in the perinatal period (P00-P96) > 2025 ICD-10-CM Codes P70-P74 – Transitory endocrine and metabolic disorders specific to newborn (P70-P74) > 2025 ICD-10-CM Codes P74 – Other transitory neonatal electrolyte and metabolic disturbances (P74) > 2025 ICD-10-CM Codes P74.4 – Other transitory electrolyte disturbances of newborn (P74.4) > 2025 ICD-10-CM Codes P74.42 – Disturbances of chlorine balance of newborn (P74.42) > 2025 ICD-10-CM Diagnosis Code P74.421 – Hyperchloremia of newborn (P74.421)

2025 ICD-10-CM Diagnosis Code P74.421 – Hyperchloremia of newborn (P74.421)

2019 – New Code2019202020212022202320242025Billable/Specific Code
  • P74.421 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM P74.421 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of P74.421 – other international versions of ICD-10 P74.421 may differ.

ICD-10-CM P74.421 is grouped within Diagnostic Related Group(s):

  • 791 Prematurity with major problems
  • 793 Full term neonate with major problems

Applicable To

  • Hyperchloremic metabolic acidosis

Type 2 Excludes

  • late metabolic acidosis of the newborn (P74.0)

Code History

  • 2019 (effective 10/1/2018): New code
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to P74.421:

  • hyperchloremic, of newborn > metabolic NEC E87.20
  • hyperchloremia > newborn, transitory P74.49
  • hyperchloremic metabolic acidosis > newborn, transitory P74.49

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