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Free Medical Coding > ICD10 CM > 2025 ICD-10-CM Codes > 2025 ICD-10-CM Codes C00-D49 – Neoplasms (C00-D49) > 2025 ICD-10-CM Codes D49-D49 – Neoplasms of unspecified behavior (D49) > 2025 ICD-10-CM Codes D49 – Neoplasms of unspecified behavior (D49) > 2025 ICD-10-CM Diagnosis Code D49.9 – Neoplasm of unspecified behavior of unspecified site (D49.9)

2025 ICD-10-CM Diagnosis Code D49.9 – Neoplasm of unspecified behavior of unspecified site (D49.9)

2016201720182019202020212022202320242025Billable/Specific Code
  • D49.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM D49.9 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of D49.9 – other international versions of ICD-10 D49.9 may differ.

ICD-10-CM D49.9 is grouped within Diagnostic Related Group(s):

  • 826 Myeloproliferative disorders or poorly differentiated neoplasms with major o. R. Procedures with mcc
  • 827 Myeloproliferative disorders or poorly differentiated neoplasms with major o. R. Procedures with cc
  • 828 Myeloproliferative disorders or poorly differentiated neoplasms with major o. R. Procedures without cc/mcc
  • 829 Myeloproliferative disorders or poorly differentiated neoplasms with other procedures with cc/mcc
  • 830 Myeloproliferative disorders or poorly differentiated neoplasms with other procedures without cc/mcc
  • 843 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses with mcc
  • 844 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses with cc
  • 845 Other myeloproliferative disorders or poorly differentiated neoplastic diagnoses without cc/mcc

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2016 (effective 10/1/2015): No change
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to D49.9:

  • neoplastic disease NOS (see also Neoplasm) > in (due to) E22.0
  • neoplastic disease > in G31.2
  • neoplastic disease > in E03.9
  • neoplastic disease > root or plexus NOS (in) G54.9
  • in neoplastic disease (due to) > Dermatomyositis (acute) (chronic)
  • in neoplastic disease > Dermatopolymyositis M33.90
  • neoplastic disease (see also Neoplasm) > in (due to) (with) P11.1
  • neoplastic disease > in
  • neoplastic disease > in (due to)
  • paraneoplastic > Neuromyopathy G70.9
  • paraneoplastic (sensorial) (Denny Brown) > Neuropathy, neuropathic G62.9
  • neoplastic disease > in (due to) C41.9
  • carpus > neoplastic disease D49.9
  • clavicle > neoplastic disease D49.9
  • femur > neoplastic disease D49.9
  • fibula > neoplastic disease D49.9
  • finger > neoplastic disease D49.9
  • humerus > neoplastic disease D49.9
  • ilium > neoplastic disease D49.9
  • ischium > neoplastic disease D49.9
  • metacarpus > neoplastic disease D49.9
  • metatarsus > neoplastic disease D49.9
  • multiple sites > neoplastic disease D49.9
  • neck > neoplastic disease D49.9
  • radius > neoplastic disease D49.9
  • rib > neoplastic disease D49.9
  • scapula > neoplastic disease D49.9
  • skull > neoplastic disease D49.9
  • tarsus > neoplastic disease D49.9
  • tibia > neoplastic disease D49.9
  • toe > neoplastic disease D49.9
  • ulna > neoplastic disease D49.9
  • vertebra > neoplastic disease D49.9
  • neoplastic disease > in B99
  • neoplastic disease > in (due to) G62.1
  • neoplastic disease > in

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