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Free Medical Coding > ICD10 CM > 2025 ICD-10-CM Codes > 2025 ICD-10-CM Codes C00-D49 – Neoplasms (C00-D49) > 2025 ICD-10-CM Codes C81-C96 – Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96) > 2025 ICD-10-CM Codes C88 – Malignant immunoproliferative diseases and certain other B-cell lymphomas (C88) > 2025 ICD-10-CM Diagnosis Code C88.4 – Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] (C88.4)

2025 ICD-10-CM Diagnosis Code C88.4 – Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] (C88.4)

2016201720182019202020212022202320242025Billable/Specific Code
  • C88.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
  • The 2024 edition of ICD-10-CM C88.4 became effective on October 1, 2022.
  • This is the American ICD-10-CM version of C88.4 – other international versions of ICD-10 C88.4 may differ.

ICD-10-CM C88.4 is grouped within Diagnostic Related Group(s):

  • 820 Lymphoma and leukemia with major o. R. Procedures with mcc
  • 821 Lymphoma and leukemia with major o. R. Procedures with cc
  • 822 Lymphoma and leukemia with major o. R. Procedures without cc/mcc
  • 823 Lymphoma and non-acute leukemia with other procedures with mcc
  • 824 Lymphoma and non-acute leukemia with other procedures with cc
  • 825 Lymphoma and non-acute leukemia with other procedures without cc/mcc
  • 840 Lymphoma and non-acute leukemia with mcc
  • 841 Lymphoma and non-acute leukemia with cc
  • 842 Lymphoma and non-acute leukemia without cc/mcc
  • 974 Hiv with major related condition with mcc
  • 975 Hiv with major related condition with cc
  • 976 Hiv with major related condition without cc/mcc

Applicable To

  • Lymphoma of skin-associated lymphoid tissue [SALT-lymphoma]
  • Lymphoma of bronchial-associated lymphoid tissue [BALT-lymphoma]

Type 1 Excludes

  • high malignant (diffuse large B-cell) lymphoma (C83.3-)

Code History

  • 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
  • 2016 (effective 10/1/2015): No change
  • 2017 (effective 10/1/2016): No change
  • 2018 (effective 10/1/2017): No change
  • 2019 (effective 10/1/2018): No change
  • 2020 (effective 10/1/2019): No change
  • 2021 (effective 10/1/2020): No change
  • 2022 (effective 10/1/2021): No change
  • 2023 (effective 10/1/2022): No change
  • 2024 (effective 10/1/2023): No change
  • 2025 (effective 10/1/2024): No change

Diagnosis Index entries containing back-references to C88.4:

  • BALT > Lymphoma (of) (malignant) C85.90
  • bronchial-associated lymphoid tissue [BALT-lymphoma] > Lymphoma (of) (malignant) C85.90
  • extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] > Lymphoma (of) (malignant) C85.90
  • MALT > Lymphoma (of) (malignant) C85.90
  • mucosa-associated lymphoid tissue [MALT-lymphoma] > Lymphoma (of) (malignant) C85.90
  • SALT > Lymphoma (of) (malignant) C85.90
  • skin-associated lymphoid tissue [SALT-lymphoma] > Lymphoma (of) (malignant) C85.90

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