- E16.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
- The 2024 edition of ICD-10-CM E16.1 became effective on October 1, 2022.
- This is the American ICD-10-CM version of E16.1 – other international versions of ICD-10 E16.1 may differ.
ICD-10-CM E16.1 is grouped within Diagnostic Related Group(s):
- 643 Endocrine disorders with mcc
- 644 Endocrine disorders with cc
- 645 Endocrine disorders without cc/mcc
Applicable To
- Functional hyperinsulinism
- Functional nonhyperinsulinemic hypoglycemia
- Hyperinsulinism NOS
- Hyperplasia of pancreatic islet beta cells NOS
Type 1 Excludes
- diabetes with hypoglycemia (E08.649, E10.649, E11.649, E13.649)
- hypoglycemia in infant of diabetic mother (P70.1)
- neonatal hypoglycemia (P70.4)
Code History
- 2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
- 2016 (effective 10/1/2015): No change
- 2017 (effective 10/1/2016): No change
- 2018 (effective 10/1/2017): No change
- 2019 (effective 10/1/2018): No change
- 2020 (effective 10/1/2019): No change
- 2021 (effective 10/1/2020): No change
- 2022 (effective 10/1/2021): No change
- 2024 (effective 10/1/2022): No change
Diagnosis Index entries containing back-references to E16.1:
- hyperinsulinism > in (due to) (with) P11.1
- posthypoglycemic (coma) > Encephalopathy (acute) G93.40
- encephalopathy > with E15
- ectopic > Hyperinsulinism (functional) E16.1
- beta > pancreatic islet cells E16.9
- functional, nonhyperinsulinemic > Hypoglycemia (spontaneous) E16.2
- infantile > Hypoglycemia (spontaneous) E16.2
- reactive (not drug-induced) > Hypoglycemia (spontaneous) E16.2